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If you're tired of wasting your time and money on products that just don't work, then you've come to the right place!


Research Verified® was created to help you find the best possible product on the market, based on extensive research. Our team at Research Verified® concentrates on the clinical data and actual science to make sure you get the most effective varicose vein and vascular health supplement on the market, hands down.

We will guide you through our process of what to look for and what to stay away from. At the end of this page you will have a firm understanding of which varicose vein supplement is going to help you and why.

Most Varicose Vein Supplements Simply Do Not Work


Countless companies and marketers are jumping on the herbal supplement niche to create their own version of a varicose vein supplement that "really works". Most of them disregard the research and put together an inferior product to try to cash in on this new niche. Most of these products don't work and can even be dangerous, especially when dealing with supplements.

Unfortunately, you can't always trust what it says on the label. Most varicose vein supplements do not contain what's actually on the label. As was recently stated on the world famous TV doctor's show about dietary supplements, "Sometimes 9 out of 10 samples in the lab have been adulterated". (Which is why third party testing is important, yet most companies don't do it.)

There are literally hundreds of varicose vein supplements out there all claiming to have the best product. But how do you know who to trust? And more importantly, how do you know which product is actually going to work for you? With all the products out there, you want to make sure you get the highest quality product available, period.

We at Research Verified® tried to make your decision simple. How? Well, we did all the research for you. Let us show you what we discovered below...

How Do You Find a Varicose Vein Supplement That Will Actually Work?


We understand that your end goal is varicose vein support, management and prevention for optimal vascular health. Plain and simple. And you want the best varicose vein product to help you do that.

You don't want to waste your time or money on something that won't work. So, how do you find a varicose vein supplement that will actually help you achieve the ultimate vein and vascular health possible?

Stick to these 3 Guidelines:

  1. Make sure it provides a  total care system for optimal varicose vein and vascular health support, management and prevention  containing ingredients that have been proven effective in reducing inflammation and swelling, reducing pain, improving blood circulation, strengthening capillaries, shrinking blood vessels and reducing appearance of unhealthy veins.
  2. Make sure it meets all of  Research Verified's criteria  for effectiveness, safety and security. Our team put together a list of requirements to ensure you get the highest quality product.
  3. Make sure it has a rock solid  365 day money back guarantee  which shows how much confidence the manufacturers have in their own product.


1 It Must Conform to The Specific Criteria & The Clinical Studies

Here's what to watch out for when buying a varicose vein supplement. We'll start with the most important criteria to look out for.

Here are The Top Criteria:

  • It must be a  multi-action formula for providing optimal vascular health support and management plus varicose vein symptom relief and prevention.
  • It must contain  Witch Hazel, Horse Chestnut, Butcher's Broom, Ginger plus flavonoids Diosmin, Hesperidin and Rutin.
  • It must have no additives, preservatives or any other artificial ingredients.
  • It must be of the same purity of ingredients found effective in clinical studies and provide both internal (supplement) and external (cream) treatment options.

So, check the label to make sure it meets all of these criteria. If it doesn't, don't buy it!

( click here to see our Vari Relief label, or  click here to see our Vari Relief Cream label)

The varicose vein supplement we recommend meets all the criteria!

Apart from the above criteria, here are other factors you want to look out for:

  • Look out for false claims and unsupported facts.
  •  Make sure the supplement is made in the USA in an FDA registered laboratory.
  •  Make sure the manufacturing facility is cGMP certified.
  •  Finally, make sure it complies with the US Pharmacopeia's quality standards.

Important Notes

  • * 1. Make sure it contains clinically proven ingredients for optimal vascular health support, management and symptom relief and prevention for varicose veins. Despite what you see on other sites, the  ingredients do matter Some combinations will be ineffective and others can be dangerous.
  • * 2. Make sure it contains the key ingredients of Witch Hazel, Horse Chestnut, Butcher's Broom, Ginger and a range of flavonoids including Diosmin, Hesperidin and Rutin to  provide a total care solution for treating varicose veins and promoting ultimate vascular health A combined supplement (internal healing) and cream (external healing) option is the best. Don't settle for less.

What's In The Clinical Studies:

The varicose vein supplement we recommend is a unique formulation which contains the most effective clinically proven ingredients as used in a variety of clinical studies. It provides the ultimate combination (supplement and cream ) for the most effective internal and external healing solution.

It's important to note that this unique supplement provides a  total care system for treating vascular health. Its 100% natural ingredients shrink blood vessels, reduce inflammation and swelling, strengthen capillaries and capillary walls, improves blood circulation and flow, cleanse toxins and waste from veins, reduces pain associated with varicose veins and helps prevent them. There is nothing else on the market that provides the range of benefits found in this unique blend of ingredients.

Many clinical studies on vascular health, published in a range of Journals and Articles, have demonstrated several key ingredients that play a vital role in treating varicose veins and associated symptoms.

Extensively Researched Ingredients Proven To Treat Varicose Veins

Each ingredient was hand-picked by a team of medical doctors & scientific researchers, based on clinical data, designed to provide optimal vascular health and get results faster than any other supplement available.

(click ingredient name to open)

Vari Relief Capsules Formula (click to see ingredients)
(click ingredient name to open)
Witch Hazel - Leaf and Bark  (Hamamelis)

Witch Hazel produces astringent tannins that can be used to treat the inflammation and swelling associated with varicose veins, by working to shrink blood vessels. Witch hazel not only works to tighten stretched veins and repair vessel strength, but also alleviates pain associated with varicose veins. Several studies have demonstrated its powerful antioxidant and anti-inflammatory properties that influence the positive effects of this herb.

  • 1. MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Altern Med Rev. 2001 Apr;6(2):126-40.
  • 2. Steven Foster, Witch hazel, Hamamelis virginiana, Article and Photos, Steven Foster Group], retrieved April 14, 2012
  • 3. Witch Hazel Overview Information, WebMD, accessed April 14, 2012.
  • 4. Michael C. Bingham, Which Witch Is Witch Hazel (and Which Dickinson Makes It)?, Connecticut Business Journal, 20 October 1997.
Horse Chestnut Seed  (Aesculus hippocastanum)

Horse Chestnut produces Aescin which is effective in treating vein problems, specifically when the veins do not efficiently return blood from the legs to the heart. Aescin appears to reduce swelling, inflammation and improves blood circulation, especially when used in conjunction with other ingredients, which contain tannins and flavonoids.

  • 1. Aesculus hippocastanum (Horse chestnut). Monograph. Altern Med Rev. 2009 Sep;14(3):278-83. Review. Arcangeli P. Pycnogenol in chronic venous insufficiency. Fitoterapia. 2000;71:236-44.
  • 2. MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Altern Med Rev. 2001 Apr;6(2):126-40.

Diosmin is a flavonoid found in citrus fruits, which has been used for many years to treat conditions associated with vein health. Its anti-inflammatory properties shrink problematic veins and restore normal vein function. Diosmin promotes healthy blood flow and circulation maintaining tone and elasticity of veins which is key to sustained vascular health.

  • 1. MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Altern Med Rev. 2001 Apr;6(2):126-40.
  • 2. New Dietary Ingredients in Dietary Supplements, U. S. Food and Drug Administration Center for Food Safety and Applied Nutrition Office of Nutritional Products, Labeling, and Dietary Supplements February 2001 (Updated September 10, 2001).
Ginger Root (Zingiber officinale)

Ginger is a popular herb well known for its powerful anti-inflammatory qualities. Its warming effects promote good circulation flushing out toxins in the process. Additional benefits have been shown to reduce the likelihood of clotting by reducing platelet stickiness which ultimately, will keep the cardiovascular system much healthier.

  • 1. O'Hara, Mary; Kiefer, David; Farrell, Kim; Kemper, Kathi (1998). "A Review of 12 Commonly Used Medicinal Herbs". Archives of Family Medicine 7 (6): 523–536.
  • 2. University of Maryland Medical Centre (2006)."Ginger". Retrieved 2 August 2007.

Hesperidin is a flavonoid commonly found in citrus fruits and can be used in conjunction with Diosmin to treat venous (vein) insufficiency. It contains anti-inflammatory properties and has been shown to reduce the permeability of capillaries. Flavonoids are believed to provide support for capillary fragility, which may be caused by injury or disease. Hesperidin protects blood vessels against the harmful effects of free radicals and strengthens veins.

  • 1. MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Altern Med Rev. 2001 Apr;6(2):126-40.
  • 2. Benavente-García, O.; Castillo, J. (2008). "Update on Uses and Properties of Citrus Flavonoids: New Findings in Anticancer, Cardiovascular, and Anti-inflammatory Activity". Journal of Agricultural and Food Chemistry 56 (15): 6185–205.
Oats (Avena sativa)

Avena sativa, commonly known as oats, contains a range of medicinal elements. Alongside its cholesterol reducing benefits, its diuretic qualities reduce fluid retention and the alkaloids it contains are known to cause a relaxing action in the venous system which in turn promotes blood flow and circulation.

  • 1. "Nutrition for everyone: carbohydrates". Centers for Disease Control and Prevention, US Department of Health and Human Services. 2014.
  • 2. "Oats". World's Healthiest Foods, The George Mateljan Foundation. 2014.
  • 3. Navarra, Tova. (2004). The Encyclopedia of Vitamins, Minerals and Supplements. Second Edition.
Butcher's Broom  (Ruscus aculeatus)

Butcher's Broom contains anti-inflammatory properties and has been found by researchers to stimulate vasoconstriction, beneficial for treating circulatory conditions. It contains two main active 'saponin' elements - neoruscogenin and ruscogenin. These elements are known to benefit venous conditions by acting as agents to tighten blood vessels and capillaries. European hospitals commonly use Butcher's Broom to prevent the development of clots after surgical procedures. Butcher's Broom promotes vein strength and allows for improved blood flow.

  • 1. Vanscheidt W, Jost V, Wolna P, et al. Efficacy and safety of a Butcher's broom preparation (Ruscus aculeatus L. extract) compared to placebo in patients suffering from chronic venous insufficiency. Arzneimittelforschung. 2002;52:243-250.
  • 2. MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Altern Med Rev. 2001 Apr;6(2):126-40.
Bilberry  (Vaccinium myrtillus)

Bilberry is a small fruit, similar to the Blueberry. It is recognised for its strong antioxidant properties and ability to strengthen blood vessels, which in turn encourages better circulation and blood flow.

  • 1. Persson I.A., Persson K., Andersson R.G. Effect of Vaccinium myrtillus and its polyphenols on angiotensin-converting enzyme activity in human endothelial cells. J Agric Food Chem. 2009 Jun 10;57(11):4626-9.
  • 2. Burdulis D, Ivanauskas L, Dirse V, Kazlauskas S, Razukas A (2007). "Study of diversity of anthocyanin composition in bilberry (Vaccinium myrtillus L.) fruits" (PDF). Medicina (Kaunas) 43 (12): 971–7.
Plantain  (Plantago lanceolata)

Modern studies confirm the anti-inflammatory and antibacterial properties of plantain, with some studies suggesting that plantain extract decreases arterial blood pressure. It contains Aucubin, which has been reported to be a powerful anti-toxin. Becasue of its antibacterial quality, it is considered a safe and effective treatment for bleeding, since it quickly stops blood flow and encourages the repair of damaged tissue.

  • 1. Genetic variation in defensive chemistry in Plantago lanceolata (Plantaginaceae) and its effect on the specialist herbivore Junonia coenia (Nymphalidae). Lynn S. Adler, Johanna Schmitt and M. Deane Bowers, Oecologia, January 1995, Volume 101, Issue 1, pages 75-85
  • 2. Vogl S, Picker P, Mihaly-Bison J et al. (October 2013). "Ethnopharmacological in vitro studies on Austria's folk medicine--an unexplored lore in vitro anti-inflammatory activities of 71 Austrian traditional herbal drugs". Journal of Ethnopharmacology 149 (3): 750–71.

Rutin is a citrus flavonoid suggested to decrease capillary permeability, which thins the blood and enhances blood flow. It also contains anti-inflammatory and antioxidant properties.

  • 1. MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Altern Med Rev. 2001 Apr;6(2):126-40.
  • 2. Reporter, Daily Mail (9 May 2012). "Chemical found in apples, onions and green tea can help beat blood clots". London: Mail Online.
Mullein Leaf  (Verbascum thapsus)

Mullein leaf comes from a wildflower and has been shown to contain antibacterial, diuretic, antispasmodic, expectorant, astringent, sedative, mucilaginous, and vulnerary properties.

  • 1. Viljoen A, Mncwangi N, Vermaak I. Anti-Inflammatory Iridoids of Botanical Origin. Current Medicinal Chemistry. 2012;19(14):2104-2127.
Red Root  (Lachnanthes)

Red Root is a tall green shrub that grows in North America and has a long history of medicinal uses. It contains tannins which work to shrink tissues and reduce abnormal bleeding. Its astringent properties reduce bleeding from broken skin capillaries reducing spider veins. Furthermore, it is shown to smooth varicose veins by stimulating inter-tissue fluid circulation and increasing blood flow.

  • 1. Dandy, James Edgar. Journal of Botany, British and Foreign 70: 329. 1932.
  • 2. Robertson, Kenneth R. (2003), "Lachnanthes caroliniana", in Flora of North America Editorial Committee, eds. 1993+, Flora of North America online 26, New York & Oxford: Oxford University Press, pp. 47–48, retrieved 2008-11-17

Niacin is a B-complex vitamin that is known to reduce cholesterol and other fatty elements in the blood, by raising the amount of HDL (good cholesterol) and reducing the amount of LDL (bad cholesterol) in the blood as it flows through the veins. Studies have shown that Niacin improves blood flow in the veins and arteries, which is beneficial for treating and preventing varicose veins.

  • 1. Lamb JJ, Konda VR, Desai A, Bland JS, Tripp ML. The Effects of Tetrahydro-iso-alpha Acids and Niacin on Monocyte-Edothelial Cell Interactions and Flow-mediated Vasodilation. Global Advances in Health and Medicine. 2012;1(4):84-91. doi:10.7453/gahmj.2012.1.4.012.
  • 2. Si Y, Zhang Y, Zhao J, et al. Niacin Inhibits Vascular Inflammation via Downregulating Nuclear Transcription Factor-κB Signaling Pathway. Mediators of Inflammation. 2014;2014:263786.
Cayenne  (Capsicum annum)

Cayenne contains the active ingredient capsaicin, which is a well known warming agent known to relieve pain. It is also an excellent blood circulation stimulant ensuring optimal blood flow and nutrient delivery essential for good vascular health. Proper circulation is critical for bringing healing nutrients to damaged cells and for flushing waste from the cells. It also has anti-inflammatory characteristics that reduces swelling and antioxidant properties that prevents damage from free radicals.

  • 1. Westerterp-Plantenga, MS; Reinbach, HC; Smeets, A; Martinussen, T; Møller, P (June 2009). "Effects of capsaicin, green tea and CH-19 sweet pepper on appetite and energy intake in humans in negative and positive energy balance.". Clinical Nutrition 28 (3).
  • 2. "Nutrition Facts: Spices, pepper, red or cayenne". Nutrition Data. Condé Nast Digital. 2011
  • 3. Joseph E. Pizzorno Jr. and Michael T. Murray (2012). Textbook of natural medicine (4th ed. ed.). Edinburgh: Churchill Livingstone. p. 634.
Vari Relief Cream Formula (click to see ingredients)
(click ingredient name to open)

Petrolatum is a mineral oil jelly often used as a protective barrier to lock in moisture in the skin. It can be applied as a topical ointment due to its healing properties. The FDA has approved it as an over-the-counter skin protectant.

  • Jeong, Jeung-Tae; Kye, Young-Chul (2001). "Resurfacing of Pitted Facial Acne Scars with a Long-Pulsed Er:YAG Laser". Dermatologic Surgery 27 (2): 107–10.
  • MacEachern, William; Jillson, Otis (1964). "A Practical Sunscreen – 'Red Vet Pet'". Archives of Dermatology 89 (1): 147–50.
Anhydrous Lanolin

Anhydrous Lanolin is a natural wax secreted by the glands of wool-bearing animals, such as sheep. Touted for its hydrating properties, it is ideal for protecting, lubricating and moisturizing damaged skin and as a topical treatment for irritated skin and minor wounds. It is easily absorbed into the skin.

  • Conrad, L. I., Maso, H.F., Functional properties of lanolin derivatives in formulations. Am. Perfum. 77, 97, 1962.
  • Clark, E.W., Liquid lanolin - development, production, properties and uses. Am. Perfum. 77, 89, 1962.
Butcher's Broom (Ruscus aculeatus) Extract

This Mediterranean herb has been used medicinally for centuries. Studies have shown that it is an effective treatment for circulatory issues and their symptoms including varicose veins. Butcher's broom can shrink dilated blood vessels and also relieve the dermatitis, an itchy rash that usually accompanies varicose veins.

  • Butcher's Broom. (2011). //
  • MacKay D. Hemorrhoids and varicose veins: a review of treatment options. Altern Med Rev. (2001).

Glycerin, also known as glycerol, is a simple sugar alcohol compound derived from plants or animals that is highly hydrophilic which absorbs moisture from the air and produces the sensation of wetness on the skin. Widely used to lubricate, soothe and moisturize irritated skin or to speed up wound healing. It can help relieve some of the discomforts of varicose veins.

  • Mari FS, Nigri G, Dall'Oglio A, Cosenza UM, Milillo A, Terrenato I, Pancaldi A, Brescia A. Topical glyceryl trinitrate ointment for pain related to anal hypertonia after stapled hemorrhoidopexy: a randomized controlled trial. Dis Colon Rectum. 2013 Jun;56(6):768-73.
  • Short R, Chan J, Choi J, Egbert B, Rehmus W, Kimball A. Effects of moisturization on epidermal homeostasis and differentiation. Clin Exp Dermatol. 2007;32(1):88-90.
Oat (Avena sativa) Extract

Also known as oat straw, it contains antioxidants and are an important component for relieving varicose veins when applied directly on the affected areas, it can act as an emollient, soothing irritation and reducing inflammation.

  • Emmons CL1, Peterson DM, Paul GL. Antioxidant capacity of oat (Avena sativa L.) extracts. 2. In vitro antioxidant activity and contents of phenolic and tocol antioxidants. J Agric Food Chem. 1999 Dec;47(12):4894-8.
  • Health Benefits of Oat Straw. (2013). //
Organic Marigold (Calendula officinalis) Extract

Organic Marigold oil is used as an anti-inflammatory agent and as a remedy for healing wounds. When applied to varicose veins, Marigold can control swelling, throbbing and soothe them.

  • Duran, V; Matic, M; Jovanovć, M; Mimica, N; Gajinov, Z; Poljacki, M; Boza, P (2005). "Results of the clinical examination of an ointment with marigold (Calendula officinalis) extract in the treatment of venous leg ulcers". Int J Tissue React. 27 (3): 101–6.
  • Pommier, P., et al. (2004). Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer. J Clin Oncol. 22(8) 1447-53.
Cetyl Alcohol

Cetyl Alcohol is a fatty alcohol derived from whale oil. Used primarily as a lubricant and moisturizer in the treatment of eczema and other skin irritations and to relieve the itchiness usually accompanying varicose veins.

  • Gaul, LE (1969). "Dermatitis from cetyl and stearyl alcohols". Archives of dermatology 99 (5): 593.
  • Soga, F; Katoh, N; Kishimoto, S (2004). "Contact dermatitis due to lanoconazole, cetyl alcohol and diethyl sebacate in lanoconazole cream". Contact dermatitis 50 (1): 49–50.
Witch Hazel (Hamamelis virginiana)

Witch Hazel is a medicinal plant that has been used in healing for centuries. In addition to strengthening veins and reducing bleeding, it has astringent and anti-inflammatory properties. It is also effective as an anti-itching agent.

  • Erdelmeier, C. A. J. et al. Antiviral and Antiphlogistic Activities of Hamamelis virginiana Bark. Planta Medica, 62(1996) (3):241–245.
  • Steven Foster, Witch hazel, Hamamelis virginiana, Article and Photos, Steven Foster Group.
Bilberry (Vaccinium myrtillus) Extract

Bilberry is a fruit closely related to blueberries. It is a rich source of antioxidants and promotes vein and artery health, which is critical for healing varicose veins. They contain anti-inflammatory and astringent compounds, which help strengthen the blood vessels and relieve some of the associated symptoms of varicose veins.

  • Burdulis D, Ivanauskas L, Dirse V, Kazlauskas S, Razukas A (2007). "Study of diversity of anthocyanin composition in bilberry (Vaccinium myrtillus L.) fruits". Medicina (Kaunas) 43 (12): 971–7.
  • Facts on Bilberry. (2012). //
Aloe Vera (Aloe barbadensis) Gel

Commonly known as Aloe Vera, this is one of the most commonly used medicinal herbs. The juice from its leaves have many antibacterial properties and antifungal qualities, as well as a soothing and anti-inflammatory effects on irritated skin. The healing and rejuvenative properties of Aloe Barbadensis have been well researched.

  • Banu, A., Sathyanarayana, B., & Chattannavar, G. (2012). Efficacy of fresh Aloe vera gel against multi-drug resistant bacteria in infected leg ulcers. The Australasian Medical Journal, 5(6), 305–309.
  • Boudreau MD, Beland FA (2006). "An Evaluation of the Biological and Toxicological Properties of Aloe Barbadensis (Miller), Aloe Vera". J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 24 (1): 103–54.
Ginger (Zingiber officinale) Root Extract

Ginger is an ancient root that is prized around the world for both culinary and medicinal applications. It is known to provide an anti-inflammatory effect to relieve pain caused by varicose veins, and also to improve blood circulation, which helps cleanse the blood and promote proper nutrient delivery to all areas of the body.

  • O'Hara, Mary; Kiefer, David; Farrell, Kim; Kemper, Kathi (1998). "A Review of 12 Commonly Used Medicinal Herbs". Archives of Family Medicine 7 (6): 523–536.
  • Wood, George Bacon (1867). "XV. Ginger. Zingiber. U.S., Br". A Treatise On Therapeutics, And Pharmacology Or Materia Medica Volume 1. J. B. Lippincott & Co.
Peppermint (Mentha piperita) Essential Oil

Peppermint Essential Oil is derived from a plant that grows in primarily in Europe and North America. Peppermint oil has a host of uses for a variety of health conditions. Known primarily for its cooling effects upon the skin, it can be taken both orally and topically. Especially beneficial in bringing relief to bulging and throbbing varicose veins when applied directly on them.

  • Khanna R, MacDonald JK, Levesque BG (July 2014). "Peppermint oil for the treatment of irritable bowel syndrome: a systematic review and meta-analysis". Journal of Clinical Gastroenterology 48 (6): 505–12.
  • R. Eccles (1994). "Menthol and Related Cooling Compounds". J. Pharm. Pharmacol. 46 (8): 618–630.

Rutin is a compound found in many fruits and vegetables which is important for healthy circulation and blood vessel strength. Rutin is widely used to treat varicose veins due to the strengthening effect that it exerts on the capillaries.

  • Krewson, C. F.; Naghski, J. (2006). "Some physical properties of rutin". Journal of the American Pharmaceutical Association 41 (11): 582–7.
  • Navarro-Núñez, L.; Lozano, M. L.; Palomo, M.; Martínez, C.; Vicente, V.; Castillo, J.; Benavente-García, O.; Diaz-Ricart, M.; Escolar, G.; Rivera, J. (2008). "Apigenin Inhibits Platelet Adhesion and Thrombus Formation and Synergizes with Aspirin in the Suppression of the Arachidonic Acid Pathway". J. Agric. Food Chem. 56 (9): 2970-6.
Clove (Eugenia caryophyllus) Bud Oil

Traditionally used in Ayurvedic and Chinese medicine for pain relief. It has also been shown effective for soothing wounds and reducing inflammation.

  • Alqareer A, Alyahya A, Andersson L. (May 24, 2012). "The effect of clove and benzocaine versus placebo as topical anesthetics". Journal of dentistry 34 (10): 747–50.
  • "Clove". MedlinePlus, U.S. National Library of Medicine and National Institutes of Health. 2014. Retrieved August 18, 2014.

Similar to Diosmin, Hesperidin is another phlebotonic compound found in abundance in citrus peels and other fruits. Studies have shown that hesperidin can significantly reduce the symptoms of varicose veins.

  • Lyseng-Williamson KA, Perry CM. Drugs. 2003;63(1):71-100. Review.
  • Peterson, J. J.; Beecher, G. R.; Bhagwat, S. A.; Dwyer, J. T.; Gebhardt, S. E.; Haytowitz, D. B.; Holden, J. M. (2006). "Flavanones in grapefruit, lemons, and limes: A compilation and review of the data from the analytical literature". Journal of Food Composition and Analysis 19 (Supplement): S74–S80.

Similar to Hesperidin, Diosmin is another phlebotonic compound found in abundance in citrus peels and other fruits. Studies have shown that Diosmin can significantly reduce the symptoms of varicose veins. Diosmin promotes healthy vein function and improves the blood flow and reduces pain and inflammation in varicose veins.

  • Katherine A. Lyseng-Williamson and Caroline M. Perry. Micronised Purified Flavonoid Fraction. (2003). Adis Intl. Ltd.
  • Alternative medicine Review. (2004). Diosmin: Monograph. Thorne Research Inc.
Psyllium Husk

Psyllium Husk is a natural fiber derived from the Plantago ovata plant, specifically from the husks of the plant’s seeds. Psyllium benefits the whole body, including varicose veins. Constipation can cause varicose veins, by ingesting Psyllium and thereby improving bowel movements, optimal vascular health is achieved.

  • Alberts DS, Martínez ME, Roe DJ, et al. Lack of effect of a high-fiber cereal supplement on the recurrence of colorectal adenomas. N Eng J Med. 2000;342(16):1156-1162.
  • Anderson JW, Allgood LD, Lawrence A, et al. Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials. Am J Clin Nutr. 2000;71:472-479.
Vitamin K-1 (Phylloquinone)

Vitamin K-1 (Phylloquinone) is an essential enzyme found naturally in a wide variety of plants. Research suggests that it has antioxidant properties and the ability to reduce blood clotting, especially important when treating varicose veins.

  • Haroon Y, Shearer MJ, Rahim S, Gunn WG, McEnery G, Barkhan P (June 1982). "The content of phylloquinone (vitamin K1) in human milk, cows' milk, and infant formula foods determined by high-performance liquid chromatography". J. Nutr. 112 (6): 1105–17.
  • "WHO Model List of Essential Medicines: 18th list". World Health Organization. October 2013. Retrieved 22 April 2014.

Melatonin is a natural human hormone that not only works with the body's own sleep-wake cycle (circadian rhythm) but also protects the skin by acting as a powerful healing antioxidant, helping to restore, firm, and smoothen it. Studies have shown that Melatonin rejuvenates your skin at the cellular level by stimulating the growth of fibroblasts, which are the cells that produce collagen and elastin. Your skin’s whole structural support depends on collagen and elastin. Other studies have also shown Melatonin to be a stronger free radical scavenger than even vitamins C and E. Topical Melatonin is ideal for skin renewal and repair, damaged by varicose veins since it can penetrate the tough outer layer of your skin (the stratum corneum). Melatonin is also an anti-aging hormone that is effective for reducing and helping prevent sun damage and wrinkles.

  • Ardura J, Gutierrez R, Andres J, Agapito T (2003). "Emergence and evolution of the circadian rhythm of melatonin in children". Horm. Res. 59 (2): 66–72.
  • Fischer T W, Greif C, Fluhr J W, Wigger-Alberti W, Elsner P. “Percutaneous penetration of topically applied melatonin in a cream and an alcoholic solution.” Skin Pharmacol Physiol 2004: 17: 190–194.
  • Fischer T W, Scholz G, Knoll B, Hipler U C, Elsner P. “Melatonin suppresses reactive oxygen species in UV-irradiated leukocytes more than vitamin C and trolox.” Skin Pharmacol Appl Skin Physiol 2002: 15: 367–373.
  • Fischer TW, Slominski A, Zmijewski MA, Reiter RJ, Paus R. “Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair.” Exp Dermatol. 2008 Sep;17(9):713-30.
  • Sack RL, Lewy AJ, Erb DL, Vollmer WM, Singer CM (1986). "Human melatonin production decreases with age". J. Pineal Res. 3 (4): 379–88.

*Disclaimer: Results of this study may not be an implication of future results.

2 Research Verified's Criteria For Effectiveness, Safety and Security

For a product to earn the Research Verified® seal of approval, it must go through a diligent research process. Every product formulated by Research Verified® must have the following criteria. If just one criterion is missing, that's not good enough for our standards.

Every Research Verified® Product Must...

  • Contain only the highest quality ingredients based on the scientific research available.
  • Contain the proper dosage and purity based on clinical studies and/or scientific research.
  • Be manufactured in the USA in an FDA-registered laboratory that is also GMP-certified.
  • Comply with the US Pharmacopeia's standards for quality and purity.
  • Be insured by a third-party monitoring company for consumer protection, such as buySAFE.
  • Only contain raw ingredients that have been third-party tested.
  • Contain no contaminants in the product that might hinder results.

If you're looking for the highest quality product available, turn to Research Verified® first instead of wasting your time on inferior products. Research Verified® is the best choice for quality and comes with a Risk-Free 365-Day 100% Money-Back Guarantee.

What We're Not

You can feel confident that you are getting the highest quality premium product available, hands down, when you buy at Research Verified®. We don't cut any corners or sacrifice quality in any way.

  • We Don't Hide Behind Our Website or Our Labels.
    Unlike many companies, Research Verified® keeps everything transparent. We explain in detail the research we carried out and why each product we chose is the best in its industry. We do not hide behind our labels or website. You can see the entire label of every product with the Research Verified® seal on it.
  • No False Claims or Misleading Facts.
    Research Verified® never uses false claims and does not misrepresent the facts. We'll tell you what's available, what's working, and why. We only quote from actual clinical studies. We'll tell you the facts behind the research and let you decide.
  • No Automatic Shipping or Auto-Billing.
    You can trust any order purchased from Research Verified®. We will never bill your credit card without your knowledge. We will never put you on an auto-ship program. You will be billed only when you place your order and that's it.
  • We Won't Leave You High and Dry.
    Not only do we welcome you in and encourage you to read through our research and information, we invite and welcome any questions you may have. You can email or call us any time. We are here to help you and to provide you with a superior product.

Research Verified® was created to make it easier for consumers to find a high-quality product that they trust and to ensure you get the highest quality product at the best possible price.

3 Risk Free 365 Day Money Back Guarantee

If any varicose vein supplement is going to work for you, this is it.

We are so confident that this product is going to work that we offer a full 1 year guarantee. With a 365 day money back guarantee, you can be sure that each Research Verified® product is the best and safest option available.

If you're serious about promoting optimal vascular and vein health support and management  then you should try a product that is serious about helping you achieve your goals. We did extensive research to ensure that we found the best vein health supplement on the market and are so confident that it's going to work for you, that we're offering you a full year to try it out.

How To Protect Yourself From Bad Varicose Vein Supplements

How do you, the consumer, know you're buying a quality varicose vein product? There's only one way and that's through the research. No flashy website, aggressive advertising or overzealous celebrity is going to tell you what will actually work.

Whenever there's a new "hot" product on the market, hundreds of companies and marketers jump on board to create their own version. Many times they disregard the research and put together an inferior product to try to cash in on this new niche. Most of these products don't work and can even be dangerous, especially when dealing with supplements.

Oftentimes you will see supplement manufacturers making outlandish claims that are unsupported and even claiming to have the best product. So many companies make these claims - that it's impossible for you to know who's telling the truth and who's just out to take your money. Here are some things you should look out for...

6 Things To Watch Out For When Buying a Gout Supplement:


  • 1. Look out for False Claims and Unsupported Facts. - Be cautious of products that claim to be the best and don't show you the facts behind their statements or use fake celebrity endorsements.
  • 2. Avoid "Free Trial Offers". - Many companies offer free trials to hook you in. But once you buy, they make it difficult to cancel and you are stuck paying more than you would have for a better product.
  • 3. Avoid Automatic Rebilling. - Many companies will automatically bill your credit card monthly and make it difficult to cancel. This is often bundled with "free trial" options. If they ask for your credit card details, they're probably going to charge you- make sure you know exactly what you're paying for.
  • 4. Make sure ingredients are effective and clinically proven. - If you're looking for a high quality varicose vein supplement make sure that the ingredients provide a total care solution for optimal support and management for ultimate vascular and vein health. Research Verified's VariRelief is comprised solely of ingredients whose efficacy is backed up by extensive clinical trials and research.
  • 5. Avoid Overdosing. - Some companies are so excited about new supplements that they try to pack in a very high concentration per day. But taking too much of any supplement can actually be dangerous to your health. Steer clear of supplements that push absurdly large daily doses, as taking too much of certain ingredients can be dangerous.

Why Does Research Verified® Have the #1 Varicose Vein Supplement?


Research Verified® was created to meet the needs of consumers wanting the highest quality 
product at a reasonable price with verified research and science to back it up.

Research Verified® consists of a team of researchers who look at the actual science behind what makes a product work.

We analyze the clinical studies to determine the potency and dosage that will be the most effective. We track down where the highest quality ingredients can be found. We review the CofA's (Certificate of Analysis) of every product. We make sure there are no contaminants in the product that might hinder results, like E. coli, S aureus, Pseudomonas, Yeast and Mold.

Our team at Research Verified® found the highest quality version of a detox cleansing product based on scientific data and a stringent research process.

Research Verified®: Trust & Security

  • In addition, Research Verified® has an unprecedented Risk Free - 365 day - 100% money back guarantee. You can feel confident buying from Research Verified® knowing that what you buy is actually going to work.
  • Research Verified® is partnered with buySAFE, the leading online protection agency, to give you a guaranteed shopping experience for total peace of mind over your purchase. As stated by buySAFE, Research Verified's "identity, reputation, experience, financial stability, and ability to honor their sales terms and conditions have been verified by buySAFE."

Risk Free - 365 Day - 100% Money Back Guarantee


Risk Free - 365 Day - 100% Money Back Guarantee

In Conclusion - Research Verified® Approved VariRelief Exceeds Industry Standards on Multiple Fronts


In summary, Research Verified® Approved VariRelief meets all of the criteria listed above. It's the highest quality varicose vein supplement that we've found and we highly recommend it. Here's a list of some of the criteria that it meets.

Research Verified® Approved VariRelief:

  1. Meets and exceeds all of the strict criteria above.
  2. Contains only the highest quality ingredients that have been determined to be effective in clinical studies.
  3. Is a multi-action formula to provide the ultimate support and management for vascular and vein health. An internal (supplement) and external (cream) care solution is the best.
  4. Made in an FDA registered, cGMP certified lab that complies with the US Pharmacopeia's quality standards.
  5. Insured by buySAFE for maximum consumer protection.
  6. Third party tested and contains no contaminants in the product that might hinder results.
  7. And has a Risk Free - 365-Day - 100% Money Back Guarantee.

We understand that you have a choice when purchasing supplements. At Research Verified®, our goal is give you the best varicose vein supplement possible from a trusted and verified source.

We are thrilled with the results and are sure that you will be too!

So, Which Varicose Vein and Vascular Health Supplement Should You Buy Now?

We recommend getting the Research Verified® Approved VariRelief 6 bottle package because real and effective vascular and vein health support and symptom management takes time. It meets all of the above criteria and is guaranteed to work - or your money back - up to 365 days.

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