Supplements aren’t just for meeting your vitamin goals. They can also play a role in how you feel each day. Whether it’s stress from work, restless nights, or that mid-afternoon slump that won’t quit, your mood can take a hit for many reasons. While lifestyle factors like diet, exercise, and sleep are key, certain nutrients and herbal ingredients can help support a more balanced, positive outlook.
In this post, we’ll explore some of the best supplements for mood support, from calming minerals like magnesium and GABA to natural ingredients like turmeric and probiotics. We’ll also look at a few science-backed formulas, such as Research Verified Anxiety Relief and Research Verified Sleep Aid, that combine science-backed ingredients for comprehensive support.
*Disclaimer: This post does not serve as medical advice. Supplements should only be taken with guidance from a qualified health care professional.
Popular Mood-Boosting Nutrients
When it comes to mood support, some supplements stand out for a reason. These go-to nutrients help calm your nerves, ease tension, and keep your outlook positive.
Magnesium
Magnesium is an essential mineral, meaning that your body needs it but cannot create it. Therefore, your magnesium requirements need to be met by your diet. Yet, despite magnesium being present in many foods, several factors such as highly processed diets, low vegetable consumption, and soil depletion contribute to low intake. Low levels of magnesium are linked to anxiety, depression, irritability, and mood swings, whereas supplementation has been shown to have positive effects on these mental states (1,2). This can be explained (at least partially) by magnesium’s roles in regulating neurological processes and balancing neurotransmitters such as serotonin and GABA, both of which are associated with feelings of calm and happiness (3).
GABA
As briefly mentioned above, GABA is a neurotransmitter, meaning that it’s a chemical messenger in the body. GABA (gamma-aminobutyric acid) is the brain’s main calming neurotransmitter, helping to reduce neural excitability and promote relaxation. It plays a key role in regulating mood, sleep, and stress, and low levels are linked to anxiety, depression, and insomnia.
GABA supplements are designed to support this natural calming process. While the body produces GABA on its own, supplementing may help promote relaxation, reduce stress, and improve sleep quality, especially in situations where anxiety or restlessness is affecting daily life (4). Many people find that GABA works best when paired with other mood-supporting nutrients like magnesium or adaptogenic herbs, creating a synergistic effect that helps the mind feel more balanced.
Ashwagandha
Another well-known mood-supporting nutrient, ashwagandha is an adaptogenic herb that helps the body manage stress. Traditionally used in Ayurvedic medicine, it supports energy levels, mental clarity, and overall resilience. Research suggests that ashwagandha may reduce anxiety and promote relaxation by helping to balance cortisol, the body’s primary stress hormone (5).
Often Overlooked Mood Helpers
Some ingredients don’t always get the spotlight for mood support, but they can make a big difference. These less obvious options support energy, inflammation balance, and even gut health, all of which affect how you feel.
Probiotics
Though often associated with gut health, clinical studies show that probiotics can help improve low mood, reduce anxiety, and support emotional well-being. They affect mood through the gut-brain axis, which is a communication network between the digestive system and the brain. The interesting thing is that even in healthy individuals, probiotic use has demonstrated an improvement in mood (6). The gut is where most of the body’s serotonin (also known as the ” happy hormone”) is produced which might be able to partially explain why improving gut health with probiotics has a noticeable effect on mood.
Turmeric
Turmeric is most often praised for its anti-inflammatory benefits, but that’s far from the complete picture of this spice’s potential. Curcumin, the active compound in turmeric, is associated with brain, heart, gut, and joint health, as well as mood regulation. Studies have found that Curcumin helps fight depression, possibly due to its anti-inflammatory effects (7).
Targeted Mood Support Formulas
Sometimes, a combination of ingredients works better than any single nutrient. These science-backed formulas are designed to support relaxation, stress relief, and better sleep, helping you feel your best more consistently.
Research Verified Anxiety Relief
For all-day mood support, Research Verified offers Anxiety Relief (Day) and Anxiety Relief Night. Both formulas are designed to help calm overactive neurotransmitters, ease the physical signs of anxiety, and support healthy serotonin levels. The Day formula includes magnesium and other soothing ingredients to promote calm focus without drowsiness, while the Night formula encourages relaxation and restful sleep for a more peaceful mind.
Research Verified Sleep Aid
Getting enough sleep is one of the most important parts of maintaining a balanced mood, yet it’s often the first thing to slip when stress levels rise. Research Verified Sleep Aid combines natural ingredients like valerian root, melatonin, magnesium, and chamomile to help your body and mind unwind at night. This formula promotes restful sleep without grogginess the next morning, helping you wake up refreshed and ready to face the day with a clearer, calmer mindset.
Research Verified Energy Booster
Feeling low on energy can directly impact your mood. When fatigue sets in, patience runs thin and motivation fades. Research Verified Energy Booster combines essential B vitamins with adaptogens like Rhodiola and Ashwagandha to support steady energy and balanced stress response throughout the day. Instead of relying on caffeine or quick fixes, this formula helps your body produce natural energy while supporting focus, endurance, and emotional resilience.
Addressing the Bigger Picture
While supplements can do a lot to support mood, it’s important to remember that how you feel often reflects what’s happening in your body. Low energy, poor sleep, hormonal shifts, or even joint discomfort can all take a toll on your emotional well-being. Sometimes, improving mood means addressing the root cause — whether that involves supporting hormonal balance during menopause, improving joint comfort, or promoting better digestive health. When your body feels good, your mind often follows.
Conclusion
Supporting your mood naturally doesn’t have to be complicated. Whether you’re adding a single supplement or trying a complete formula, these nutrients can help you feel calmer, more centered, and better equipped to handle life’s daily stresses. That said, supplements work best as part of a bigger picture. Therapy, mindfulness practices, regular exercise, and quality sleep all play an important role in emotional well-being. Together, they can help you build a foundation for a steadier, more positive mood every day. Small, consistent steps toward better health can make a big difference in how you feel every day.
Give Your Mood The Support It Deserves → Explore Research Verified Supplements
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